![]() ![]() Common batten spacing ranges from 12 inches to 24 inches apart. What is typical roof batten spacing? The typical roof batten spacing varies depending on the roofing material and regional building codes. Measure the width of the roof, and then divide it by the desired batten spacing to determine the number of battens required across the roof. You’ll get the number of rafters needed for your roof.How do you calculate roof batten spacing? To calculate roof batten spacing, you need to consider the desired spacing between each batten. ![]() After getting the answer, add 1 for the ‘0’ rafter and multiply it by 2. So the first thing you need to do is convert 30 ft to inches.Ĥ0ft x 12″ = 480″ (length in inches) ÷ 24″ on-center = 20 rafters. Lastly, multiply the number of rafters by 2 to get both sides of the roof or the roof’s slopes.įor example, your house is 40 feet long with a 24″ rafter spacing. After doing this, add 1 for the ‘0’ rafter. ![]() Then, you use the size of the roof’s length and divide it by the rafter spacing. The first thing to do is find the measurements, including the roof’s length and overhang or rafter spacing. But you may also use a manual estimation using a standard calculator or pencil and paper. It may be done using rafter calculators if you want a more straightforward method. In addition, the 2″×4″ lumber may span from 7 to 9 feet.Ĭalculating the estimated number of rafters needed for your roof rafters is important. Likewise, a 2″×10″ lumber may span from 16 to 23 feet, while a 2″×12″ lumber may span from 18 to 27 feet. In general, a 2″×6″ lumber may span from 10 to 15 feet, while a 2″×8″ lumber may span from 13 to 19 feet. There’s also a 2″×4″ lumber, but it’s not commonly used in building. The most common available lumber sizes used in roof framing include 2″×6″, 2″×8″, 2″×10″, 2″×12″, and 2″×14″ used in roof framing. What Size Of Lumber Do You Need For Roof Rafters? It may also depend on other factors, including the pitch or slope of roof, roof sheating, grade of timber, lumber size, wood species, snow load, live load, and rafter spacing. In addition, rafter sizing is expressed as a ratio of the roof’s rise to the run (half of the distance) or a fraction of the rise over the run.ĭepending on your roof’s structure and overall size, the sizes of lumber you need for your roof rafters will vary. The roof rafter span is commonly measured by the distance of the rafter projection horizontally from the ridge to the supporting outside wall plate’s outer edge. In general, rafter sizing refers to the thickness and depth range of the specific lumber used for the roof rafter project. Related: Complete Guide to Setting Up Roof Trusses You may decrease the rafter beam space but never increase the rafter beam spacing. In general, a rafter beam spacing should be no more than 16″ apart from another rafter beam. Rafter beams are exposed horizontal structural elements you see in the ceiling designed to support the weight of the building’s roof, transferring the load to a vertical structural part. In general, constructions often use the 4ft to 12 ft rafter spacing for a pole barn. It typically depends on the specifications of the building and the preference of the owner. There is no standard measurement used in rafter spacing for a pole barn. The deflections range from L/∆=180 and L/∆=240. Live and snow loads range from 10 to 70psf (per sq ft), with dead loads ranging from 10 to 20psf. Roof joist spacing has requirements or factors, including the rafter size, rafter span, thickness, wood species, grade, thickness, wind and snow loads, deflection, and location. Roofing joists also join the building’s opposite walls to support the floor above and the ceiling by transferring the roof’s weight to the vertical columns and into the foundation. Roof Joist Spacing GuideĪ roofing joist is a parallel horizontal member or beam that runs across an open space, which can either be laid pitched or flat, exposed or concealed, depending on the construction. In addition, the standard roof rafter spacings commonly used for most building structures are 16″ and 24″. However, the structural engineer may determine other roof rafter spacing measurements, and these may vary depending on the contributing factors affecting it. The International Residential Building Code (IRC), which is the basis of most North America’s building coide, identifies these standard industry measurements. The standard roof rafter spacings measured on-center are 12″, 16″, 19.2″, and 24″. Rafter Spacing Chart Source: lincoln.ne.gov What Is The Standard Roof Rafter Spacing? Still, it’s best to follow the guidelines provided by the Building Code or a Structural Engineer to prevent unnecessary calculation errors and ensure a local Building Department approves it. Remember that using this rafter spacing calculator may provide an accurate estimate. ![]() Best Lawn Care Service for Service Dogs.Lighted Magnifying Glass That Stays Put. ![]()
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![]() ![]() At 24 years of age.įunnily enough, I’m able to colour match other people quickly and well. Winter may call for a lighter shade with more hydration, while summer may call for a deeper shade with more nourishing ingredients.Confession: I have a diploma in makeup artistry and an almost decade-old beauty channel on YouTube, and I only just found out whether my skin undertone is warm or cool. You can also switch your foundation formula and shades up depending on the season, or what your skin is craving. Are you looking for a triple dose of skincare with your foundation? Even Better Clinical Serum Foundation is a full coverage, matte finish foundation that visibly improves skin with three potent serum technologies. Is SPF key, and are you looking for a foundation that helps with dark spots over time? Even Better Makeup does just that, with a moderate coverage and natural finish. Shade is of the utmost importance, but formula plays a large factor in your perfect foundation as well. ![]() Also keep in mind that whenever a formula is different, the same shade name can look slightly different based on the interaction of its ingredients. ![]() They can be a helpful guide, but if you want to get it right off the get-go, we always recommend color-matching by a consultant, which is a free service. Shade names like espresso or beige are not universal to all brands or even amongst the different foundation types within the same brand. You know that expression “never judge a book by its cover”? That applies to how to find the right foundation shade, too. You can also try out our virtual try-on experience to help find your foundation shade. To avoid being off base, make your foundation hunt a no-makeup excursion. The point is to match your bare skin, not your current foundation. Chances are, if you’ve already been wearing the wrong shade, you’re probably going to do it again unless you remove it completely before trying a new one. Whether you’re perusing in-store or online, a foundation skin tone chart only works if you’re showing up with bare skin. ![]() Your shade will give you confidence and look like you have nothing on. If you need to slather your face with it to look natural, chances are it’s not your perfect shade. How to find your foundation shade lies in the way it melts into your skin like it belonged there all along. The journey to finding the right foundation shade for you can seem like a lifelong one: it’s too light, too dark, too…something not quite right. Account-v2 icon account icon amex icon arrow-left icon arrow-right icon arrow-12 icon arrow-16 icon arrow-8 icon arrows-horizontal icon bag-active icon bag-with-plus icon bag icon bottle icon burger icon call icon camera icon chat-v2 icon chat icon check icon checkbox-selected-dark-v2 icon checkbox-selected-v2 icon checkbox-selected icon checkbox-unselected icon clearpay icon clock icon consultations icon copy icon facebook icon filter-on icon filter icon full-screen icon gift-icon icon green-tick icon grid icon heart icon home icon icon-close icon icon-edit icon icon-lesser icon icon-tick icon info-error icon information icon kueskipay-icon icon list icon location icon logo-clinique icon logo-clinique_old icon map icon mc icon menu-vertical icon mic-fill icon minus-12 icon minus-16 icon new-play-icon icon orders icon pause icon plus-dark icon plus-light icon plus-12 icon plus-16 icon plus-elclosed icon plus-enclosed-close icon plus-enclosed-hover icon print icon quicklook icon quickview icon radio-selected icon radio-unselected icon reward icon search-icon icon settings icon share-v2 icon share icon shipping-and-billing icon shuffle icon sign-out icon skin-school-logo icon social-facebook icon social-instagram icon social-pinterest icon social-twitter icon sound-off icon sound-on icon star-v2 icon star icon subscription icon switch-off icon switch-on icon twitter icon video-fill icon visa icon x-10 icon x-16 icon ![]() ![]() ![]() In the root of that folder is a config.xml file with the following – ![]() You can see this doc for a list of language identifiers and languages. Within that you will find folders for various languages. So first step, download the last ISO in the list below (Proofing Tools 64-bit if that’s your case).Įxtract it somewhere. (In retrospect, the screenshot above says so – “dictionaries, grammar checking, and sorting” – but I didn’t notice that initially). ![]() You see, language packs are for the UI – the menus and all that – whereas if you are only interested in spell check and all that stuff what you need is the proofing tools. That is, until I spoke to a colleague with more experience in this and realized that what I am really after is the Office 2016 Proofing Toolkit. I spent a lot of time trying to understand how to proceed with that and even downloaded the huge ISOs from VLSC but had no idea how to deploy them via ConfigMgr. I found this official doc on deploying languages and that talked about modifying the config file in ProPlus.WW\Config.xml. I don’t know much of Office so I didn’t even know where to start with. What they want is for the language to appear in this section of Office: For more information, see Add a language or set language preferences in Office.I need to deploy a language pack for one of our offices via ConfigMgr. You can change the default language for all your Office applications in the Set the Office Language Preferences dialog. Restart all Office programs for your changes to take effect.If the language accessory pack contained display and help for the language, you should see it listed here.Under Choose Display and Help languages, you can change the default display and help languages for all your Office applications.If the language accessory pack includes proofing tools for that language, the Proofing column shows Installed.Under Choose Editing Languages, make sure that the language you want to use is added to this list.Click the Office 2016 Language Preferences program that shows up.Type " Office Lang", in the Search programs and files field.Step 2: Configure Office languageĪfter you install the language accessory pack, you must configure Office for your new language preferences. Complete the installation of the new language or product using the steps above. If you have additional products and/or languages you want to install, you can re-run the install (click Reinstall) via Software Center. After the installation is complete, you will see a "successfully installed" message, as shown: In our testing, the install process only takes a few minutes time may vary depending on the language selected, speed of your network connection, and speed of your computer. If you agree the terms of the agreement, check the box and then click Continue again. Microsoft Office Language Pack 2016 - Spanish/Espa?olĬlick Continue after you selected your one product with the desired language from the list.For example, if I want to install Spanish for Microsoft Word 2016, you would select: įrom the list, select the one product that you want to install with the corresponding language. There are three products supported by this Pack: After clicking Install in Software Center, you will be prompted to select a Microsoft Product. The Microsoft Office 2016 Multi-Language Pack is available to your CAS ITS managed computer via Software Center. ![]() Step 1: In?stall the Office Multi-Language Pack from Software Center If you want the Language Pack for Office 2016 on a computer that you manage, such as a personally owned computer, refer to the Language Accessory Pack for Office 2016 article. There are two main steps to getting your additional language. The Office 2016 Multi-Language Pack includes Proofing Tools and other support for other languages. ![]() ![]() ![]() The account list in the title manager save exporter is no longer empty Seen in Wind Waker if letting the game idle on the title screen for 2 minutesįixed a crash that could happen when the path to Cemu.exe contained unicode charactersįixed a crash that could happen when loading. Fixes crash in Call of Duty: Black Ops IIįixed a logging related crash that could occur under very specific circumstances. Most notably SDL (input & motion) and wxWidgets (UI)įixed a crash in the H264 video decoder. This version (2.0) is an exception in the sense that it follows the pattern of a stable release but is very much experimental. Going forward, we simplified the versioning a bit by using shorter version numbers for stable releases (2.1, 2.2, 2.3.). Preliminary Linux builds are available on github, but be warned that they are still very rough around the edges It is important to ensure that you have legal access to these game files, respecting the rights of copyright. To use Cemu, you will need digital copies of Wii U games, often in the form of game ROMs or backup files. Can I use my own Wii U game discs with Cemu – Wii U Emulator?Ĭemu does not support playing games directly from Wii U game discs. The Cemu development team continues to improve compatibility through regular updates. Compatibility and performance can vary depending on the game and the specific configuration of your PC. While Cemu strives for compatibility with a wide range of Wii U games, not all titles may work perfectly or be fully supported. Microsoft Visual C++ 2017 X64 Redistributable: vc_redist.圆4.exeįAQs – Cemu Wii U Emulator Are all Wii U games compatible with Cemu – Wii U Emulator?.RAM: 4 GB minimum, 8 GB or more recommended.If you are looking for other alternatives to the Cemu Wii U emulator include Decaf and Citra (which is primarily a Nintendo 3DS emulator but also supports some Wii U games). This Cemu Emulator works with Microsoft versions of Windows 7, Windows 8, Windows 10, and Windows 11, both 32-bit and 64-bit. Cemu Windows PC Compatibilityĭownload the Cemu Emulator latest version for Windows PC. These packs can include higher resolutions, improved textures, anti-aliasing, and other enhancements, enabling users to customize the graphics to their liking. Graphic Packs for Visual EnhancementsĬemu Emulator for PC offers a feature called “Graphic Packs” that allows users to enhance game visuals by applying various graphical improvements. This includes features like touchscreen functionality, motion controls, and even the ability to use the gamepad as a second screen. Gamepad SupportĬemu Emulator for Windows fully supports Wii U gamepad emulation, providing an authentic experience for games that utilize the unique features of the Wii U controller. This flexibility enables players to create control configurations that suit their gaming style and preferences, ensuring a comfortable and personalized gaming experience. Customizable ControlsĬemu Wii U Emulator’s latest version supports customizable controls, allowing users to map their preferred keyboard keys or gamepad inputs to emulate the Wii U controller. ![]() Gyro functionality is emulated with limitations and can be controlled via the right mouse button. GamePad touch input can be controlled via a left mouse click. Keyboard input + USB controllers as input devices are supported. Wiimotes are emulated as well (including native support). Controller inputĬurrently, the DRC (GamePad), Pro Controller, and Classic Controller is emulated. This feature enhances the overall gaming experience, making games look more vibrant, detailed, and visually appealing. It offers the ability to render games in high-definition, providing improved visuals and sharper graphics compared to the original Wii U console. Key Features of Cemu Wii U Emulator For Windows 11/10/8/7 High-Definition Graphics With the Cemu Wii U emulator download, gamers can transform their Windows PCs into a virtual Wii U console, providing access to a wide range of Wii U games and delivering an authentic gaming experience. It provides features such as high-definition graphics, customizable controls, gamepad support, and the ability to enhance visuals through graphic packs, allowing users to enjoy Wii U games with improved performance and visual fidelity. This Wii U emulator caters to gamers and enthusiasts who wish to play Wii U games on their computers, providing a way to relive the console’s unique library.Ĭemu Wii U emulator games for Windows are primarily available and offer excellent compatibility with the Windows operating system. Cemu Wii U emulator is a popular emulator designed to replicate the Wii U gaming experience on various platforms. ![]() ![]() ![]() The Jackets will have to be sharp in their ball-screen coverages with the myriad of two-man actions the Eagles run with Post. (14.7 ppg), a crafty creator and rhythm shooter off the dribble. The Eagles surround him with guards Jaeden Zackery (12.7 ppg), a broad-shouldered, back-you-down driver, and Charleston Southern transfer Claudell Harris, Jr. His scoring and rebounding numbers (18.4 ppg, 8.1 rpg) compare favorably to Kansas’ Hunter Dickinson and Purdue’s Zach Edey, a pair of All-American and national Player of the Year candidates – and that doesn’t include his 3.3 assists, 2.1 blocks, and 47-percent shooting from three-point range.īC likes to reverse the ball through its “5” man often, meaning Post should get plenty of touches on the perimeter. North Carolina’s Armando Bacot has the gaudiest career numbers.īut the most versatile “5” man in the ACC may be Boston College’s Quinten Post, a 7-foot senior who checks all the boxes of a modern big. (photo by Courtney Metzger)ĭuke’s Kyle Filipowski has the highest draft stock. ET, Georgia Tech Sports Network from Legends Sports):Įbenezer Dowuona will get a chance to battle BC’s Quinten Post Saturday. Enjoy the top notes from my chart as the Jackets seek a sixth straight win over the Eagles (4 p.m. But in a long-overdue return to its home court, Georgia Tech (8-5, 1-1 ACC) will look to return to the win column as well. They won’t exactly need to blow the dust off their locker room stalls. Saturday afternoon game, we need everybody in Midtown,” Tech’s head coach Damon Stoudamire said. “I’m excited to see the type of energy that we come with. ![]() On Saturday they’ll again face BC (9-4, 0-2 ACC), which fell to Wake Forest on Tuesday to snap a four-game win streak. ![]() That’s the longest break in school history since 1986-87, when the Jackets went an unheard-of 43 days between home games at Alexander Memorial Coliseum.Īnd the connective thread between those streaks is the team Tech faces this weekend.ĭuring that 43-day hiatus in 1987, Georgia Tech beat Boston College 65-62 at the old Suntory Ball in Tokyo, Japan. Georgia Tech fans have had plenty of time to rest their voices.įollowing their fifth straight game away from Atlanta, the Yellow Jackets finally end a 27-day gap between home games when they return to McCamish Pavilion on Saturday. TCU experienced similar windfalls when it moved to the Big 12.Īnother possible revenue generator Turner said they’ve discussed with the ACC is University Park hosting Olympic sports competitions, taking advantage of Dallas’ central location and two major airports.By Andy Demetra | Voice of the Yellow Jackets He suggested that joining the ACC will add revenue in other forms, including the College Football Playoff fund, full revenue shares from the ACC Network, bowl payouts and financial incentives earned from the NCAA men’s basketball tournament. “At the level that we have been operating on, we’ll be increasing that over time and we’ll be getting it through the ACC also.” “We’ve never had to start with,” he said. Neither Turner, Hart nor Miller would confirm reports that SMU will decline television revenue for its first nine years in the conference, but Turner pointed out that the ACC’s average revenue distribution (nearly $40 million last year) was money SMU was not earning in its deal with the American, which distributed $8.2 million in 2022, according to tax records. ![]() ![]() ![]() Both the Lightning and headphone ports can be utilized for audio input if you have Apple smartphones with a 3.5mm audio jack. The accessories needed to use an external microphone for iPhone ® may differ depending on the model you have. Accessories are needed if connectors don't match The next step is to connect your wireless microphone for iPhone ® once it has been placed and positioned properly. ![]() Go and buy at Moman PhotoGears Store Four tips to connect wireless mic to your iPhone ® You'll get an excellent outcome if the mic is 20-30cm from your mouth and there are no clothes rubbing against it. If you want to be more creative, you can attach the mic behind a headband. If you're wearing athletic attire, this is generally the best option. The shoulder straps are another ideal spot to install a wireless lavalier microphone for iPhone ®if you're wearing a singlet. Avoid this by wearing a looser neckline or positioning the mic to the side rather than right beneath the chin. You can put the mic on a neckline, but keep in mind that if it's too close to the neck, the sound will be coloured and odd. Things can get a bit trickier if you're wearing clothing that doesn't have a firm seam for mounting, such as a singlet or t-shirt. Just make sure the mic is free of any clothes that could rub against it, or it will damage your recording. It’s simplest to place this kind of microphone to an edge of clothing, such as the seam of a button-up shirt, the lapel of a jacket, or the edge of a tie. Mounting your lav according to the types of clothing And now you can mount the windshield back. Just remove the windscreen, pinch the spiral clasp, slide your mic into the loop, and release the clasp. These clips might be a bit difficult for first-time users, but they are really simple to utilize. ![]() Attaching the lav mic to its clipĪll lavs come with a clip that you can use to attach the mic to the clothing. This will provide an uncolored and natural sound. However, as a general rule, the mic should be placed on the chest, approximately a hand's breadth (20-30cm) away from the talent’s mouth. Most lav mics have an omnidirectional capsule, which means they capture sounds from each direction equally and are hence very forgiving while recording. In order to get the finest quality from a lavalier microphone for iPhone ® Lightning, it's vital to consider its distance to your sound source. How to place lavalier microphone for iPhone ®? ![]() ![]() ![]() You can pay your monthly premium at a ConnectiCare Center and our associates will help you complete your payment online, by phone or mail. Walk Into One of Our ConnectiCare Centers: This is a good option if someone other than you makes the payment, or if you do not have time now to register.Ĭall 1-80 (TTY: 711) 24 hours a day, seven days a week.ĥ. Use this option to make a payment without registering for a website account. You will be asked to set up an account for our member website the first time you use our online payment service. ![]() You can use this link to view invoices, pay a bill or set up automatic payments. Please Note: It can take two months or more for your deductions to take effect. You can also mail or fax a letter asking to be set up for “SSA withhold.” Include your member ID number, the date and your signature, and send it to: seven days a week, and we can help set it up. You can choose this option when you enroll. You can pay your premium through automatic deduction from your monthly Social Security or Railroad Retirement Board (RRB) benefit check. Once you become a ConnectiCare member, you’ll have many convenient ways to pay your monthly premium. Representatives are available Monday through Friday from 8 a.m. If you have questions, call us at 1-80 (TTY: 711). Payments can be made using Visa, Mastercard, Discover, check, or with your bank account information. Visit a ConnectiCare Center and we’ll help you complete your payment online, by phone or mail. If you have questions, call us at 1-80 (TTY: 711 ). You must include an invoice coupon with the scan line for ConnectiCare to process your payment. Member premium payments go to a bank lockbox. You can always pay your bill by mailing a check and the invoice coupon to: Important: ConnectiCare Centers do not accept cash. Payments can be made using Visa, Mastercard, Discover, check or with your bank account information. *NOTE: To make a payment, you will need your 11-digit member ID number from your member ID card or your invoice.Ĭall 1-80 (TTY: 711), 24 hours a day, seven days a week, to use our automated payment system. You will not, however, be able to see your payment history or manage your premium payments with this option. This is a good option if someone else is paying or you do not have time now to register. Use this option to make a one-time payment on your account without registering for a website account. You can pay your invoice online by setting up automatic payments or making a one-time payment online. For individual plans purchased through Access Health CT (Connecticut exchange) or directly from ConnectiCare ![]() ![]() ![]() As a result, it is known as Newland's Law of Octaves. He linked these parallels to musical octaves. He found a pattern in every eighth element that had qualities identical to the first one. The Law of Octaves by Newland: In 1866, John Newlands, an English chemist, organized the 56 known elements in order of increasing atomic mass, beginning with hydrogen and ending with thorium. ![]() The disadvantages of Dobereiner's Triads were that these were inapplicable to elements with extremely high and low atomic masses, and this categorization was not applicable to all of the elements. Na, the middle element in this triangle, has an atomic mass of 22.99. As a result, these groupings are known as 'triads.' For example, Li has an atomic mass of 6.94, while K has an atomic mass of 39.10. He demonstrated that three elements might be arranged in a triad so that the atomic mass of the middle element is about equal to the average of the atomic masses of the other two elements. The Origins of Periodic Classificationĭobereiner's Triads: In 1817, Johann Wolfgang Dobereiner, a German scientist, attempted to organize substances having similar characteristics into groups. Scientists are looking for a systematic technique to rearrange and organize knowledge by categorizing it in order to solve this dilemma. As a result, studying the chemistry of all the different elements is extremely challenging. In the beginning, just 31 elements were known, but currently, 118 elements are known. Elements’ Positions in the Modern Periodic TableĬhemical periodicity has been described as the characteristics of elements showing a pattern and recurring variation with increasing atomic number. ![]() ![]() Illustrator also began to support TrueType, effectively ending the "font wars" between PostScript Type 1 and TrueType. With the introduction of Illustrator 7 in 1997, Adobe made critical changes in the user interface with regard to path editing (and also to converge on the same user interface as Adobe Photoshop), and many users opted not to upgrade. Versions 7–10 Adobe Illustrator 10, the last version before the Creative Suite rebrand The changes remained until CS6 when some small steps were taken to restore the app to a slightly more Mac-like interface. The interface changed radically with the following version to bring consistency between Mac and Windows computer platforms. Version 6 was the last truly Macintosh version of Illustrator. ![]() And there was no version 6 for Windows.) Version 4 was, however, the first version of Illustrator to support editing in preview mode, which did not appear in a Macintosh version until 5.0 in 1993. (There were no versions 2.0 or 4.0 for the Macintosh-although, the second release for the Mac was titled Illustrator 88-the year of its release. The next Windows version, version 4.0, was widely criticized as being too similar to Illustrator 1.1 instead of the Macintosh 3.0 version, and certainly not the equal of Windows' most popular illustration package CorelDRAW. The first version of Illustrator for Windows, version 2.0, was released in early 1989 and flopped. In the early 1990s, Adobe released versions of Illustrator for Display PostScript licensees NeXT, Digital Equipment Corporation Ultrix, Silicon Graphics IRIX, and Sun Solaris platforms, but they were discontinued due to poor market acceptance. One window would show the work in progress and the other window would show a preview of the work in progress.Īlthough during its first decade Adobe developed Illustrator primarily for Macintosh, it sporadically supported other platforms. Įarly versions of the software did not support working in preview mode and users needed to have two windows open on their desktop in order to have a live preview of their work. īyte in 1989 listed Illustrator 88 as among the "Distinction" winners of the Byte Awards, stating that with it Adobe had "pulled ahead" of previously industry-dominant competitor Aldus FreeHand. Illustrator 88, the product name for version 1.7, was released in 1988 and introduced many new tools and features. Early magazine advertisements (featured in graphic design trade magazines such as Communication Arts) referred to the product as "the Adobe Illustrator". Photoshop is primarily geared toward digital photo manipulation and photorealistic styles of computer illustration, while Illustrator provides results in the typesetting and logo graphic areas of design. Illustrator was released in early 1987, and became a commercialization of Adobe's in-house font development software and PostScript file format.Īdobe Illustrator is the companion product of Adobe Photoshop. It used lines and bézier curves to render infinitely scalable graphics. ![]() Adobe co-founder and CEO John Warnock created Illustrator in late 1986 to automate many of the manual tasks utilized by his wife, Marva, a graphic designer. History Versions 1–1.6 (Illustrator 88) ĭevelopment of Adobe Illustrator for the Apple Macintosh began in 1985 (shipping in January 1987) as Adobe's second software product after PostScript. Adobe Illustrator was reviewed as the best vector graphics editing program in 2021 by hp Magazine. The latest version, Illustrator 2024, was released on October 10, 2023, and is the 28th generation in the product line. Along with Creative Cloud (Adobe's shift to a monthly or annual subscription service delivered over the Internet), Illustrator CC was released. Originally designed for the Apple Macintosh, development of Adobe Illustrator began in 1985. Adobe Illustrator is a vector graphics editor and design program developed and marketed by Adobe. ![]() ![]() ![]() Therefore, representing this unique property of these cancers in mice is desirable in order to accurately model tumor-stroma interactions and glioma cell behavior. Gliomas do not display the well-circumscribed morphology typical of many other solid tumors. Recapitulation of the diffuse and infiltrative nature of glioma has been challenging to achieve in murine glioma models. As lower-grade gliomas invariably progress to secondary GBMs, evaluating the role of IDH directed therapy is important for patient care. Recently, mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) have been identified in the majority of lower-grade gliomas and a relatively small subset of GBMs. The genetic landscape of glioma is characterized by alterations in genes encoding epidermal growth factor receptor (EGFR), phosphate and tensin homolog deleted on chromosome 10 (PTEN), neurofibromatosis 1 (NF1), RAS, TP53, and cyclin dependent kinase inhibitor 2 (CDKN2A/B), among others, leading to cell proliferation and tumorigenesis. Recent advances in genetic engineering have enabled the production of mouse models of glioma that increasingly mimic the microenvironmental and genomic characteristics of human brain tumors. Over 80% of the genes in the mouse genome have direct human orthologs, thereby leading to adoption of the mouse as the dominant model organism for cancer biology and cancer therapy studies. In vivo cancer modeling provides numerous advantages over in vitro modeling. The intractability of these tumors highlights the need for clinical testing of new therapies that display robust activity in accurate mouse models of glioma. Despite advances in treatment, patients with GBMs have a median survival of 15 months and a 5-year survival rate of <10% with maximal resection and concomitant chemotherapy and radiation. Lower-grade gliomas tend to be slower growing and are less aggressive than higher grade gliomas, with the diagnosis of GBM conferring a dismal prognosis. Based on the histologic similarity of the tumor to glial cells, diffuse glioma is a broad term encompassing astrocytoma, oligodendroglioma, each of their anaplastic variants, and GBM. If convicted, Prine faces 10 years to life in prison.Diffuse gliomas are the most common primary tumor of the central nervous system (CNS) and are currently classified as lower-grade glioma (WHO grade II and III) or glioblastoma (GBM WHO grade IV) based on a combination of histologic and molecular features. The children were about that old, the detective replied. “That,” referred to, in Prine’s words “sexual interaction between family members.”ĭid the mom like to participate (in the incest and child rape) or just watch? “I enjoy both,” the detective replied, before asking Morton for his age preferences. “Are you into that?” Prine had written to the detective earlier. Earlier, Prine had explained in explicit detail exactly what he hoped to get out of the encounter: This case presents a world of smoke and mirrors.”Ī world of smoke and mirrors that nevertheless resolves into a pretty damning scene: Police busted Prine, carrying a pizza box, as he approached the supposed 32-year-old mother’s apartment on Nov. “It is not just officers who pose,” he told the court. ![]() Prine’s lawyer is taking the “Internet as fantasyland” defense, claiming his client was simply role-playing. hristmas”ĭetective James Morton, who posted the ad, was using the capital letters as a simple code: In pedophile circles, PTHC stands for “pre-teen hardcore.” The ad was an invitation, and Prine took Morton up on his offer. “P.hamily fun serious replies only bama won yes T.erday and kansas state lost don’t forget to H. The flurry of emails began with this message posted to the “Casual Encounters” section of Craigslist: Jurors heard opening statements yesterday in the case of Alan Preston Prine, 60, arrested last November after exchanging more than 200 emails with an undercover officer posing as a 32-year-old housewife offering up her two pre-teen kids for sex. A recent undercover sting in Mobile, Ala., provides a window into the secret world of coded language pedophiles use online. ![]() |
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